产品

本公司产品仅供体外研究使用,不用于临床诊断

Villin antibody

分类: 研究方向:
别称:VIL antibody, VIL1 antibody, Villin antibody, villin 1 antibody
货号:FNab09407反应性:Human, Mouse
宿主:Mouse验证实验:ELISA, WB, IHC, IF, IP
克隆性:monoclonal亚型:IgG1
¥2100
规格:
货期: 三个工作日+顺丰&京东快递时长
  • 产品介绍
产品名称
Villin antibody
货号
FNab09407
规格
100μg
状态
liquid
纯化方法
Protein A+G purification
纯度
≥95% as determined by SDS-PAGE
克隆性
monoclonal
亚型
IgG1
Clone ID
3D11
存储
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
免疫原信息
免疫原
villin 1
别称
VIL antibody, VIL1 antibody, Villin antibody, villin 1 antibody
UniProt ID
P09327
分子量
93 kDa
验证实验
验证实验
ELISA, WB, IHC, IF, IP
建议稀释比例
WB: 1:500-1:5000; IHC: 1:50-1:2000; IF: 1:10-1:100; IP: 1:500-1:5000
验证图片
human kidney tissue were subjected to SDS PAGE followed by western blot with FNab09407(VIL1 antibody) at dilution of 1:1000
IP Result of anti-Villin (IP:FNab09407, 4ug; Detection:FNab09407 1:300) with mouse kidney tissue lysate 4000ug.
Immunohistochemistry of paraffin-embedded human colon cancer tissue slide using FNab09407(VIL1 Antibody) at dilution of 1:50?
背景介绍
Villin 1(VIL1) is a 95-kd F-actin bundling and severing protein and its expression is restricted to epithelial cells with a brush border, like epithelial cells of the intestinal mucosa, gall bladder, renal proximal tubules and ductuli efferentes of the testis. VIL1 has been reported to be an epithelial cell-specific anti-apoptotic protein, and to have an important function in regulating actin dynamics, cell morphology, epithelial-to-mesenchymal transitions, cell migration and cell survival. In addition, VIL1 is a useful diagnostic marker for of various cancer, like cervical and endometrial adenocarcinomas, renal cell carcinoma. VIL1 was recently identified as a novel biomarker predictive for postoperative recurrence and poorer prognosis of high serum AFP associated HCC.