产品
本公司产品仅供体外研究使用，不用于临床诊断
WT1 antibody
¥1900
规格：
货期：
三个工作日+顺丰&京东快递时长
- 产品名称
- WT1 antibody
- 货号
- FNab09528
- 规格
- 100μg
- 状态
- liquid
- 纯化方法
- Immunogen affinity purified
- 纯度
- ≥95% as determined by SDS-PAGE
- 克隆性
- polyclonal
- 亚型
- IgG
- 存储
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
免疫原信息
- 免疫原
- Wilms tumor 1
- 别称
- GUD antibody, WAGR antibody, Wilms tumor 1 antibody, Wilms tumor protein antibody, WIT 2 antibody, WT1 antibody, WT33 antibody
- UniProt ID
- P19544
- 分子量
- 52 kDa
验证实验
- 验证实验
- ELISA, WB, IHC, IF, IP
- 建议稀释比例
- WB: 1:500-1:5000; IHC: 1:50-1:500; IF: 1:20-1:200; IP: 1:500-1:5000
验证图片
A549 cells were subjected to SDS PAGE followed by western blot with FNab09528(WT1 antibody) at dilution of 1:1000
IP Result of anti-WT1 (IP:FNab09528, 4ug; Detection:FNab09528 1:1000) with mouse kidney tissue lysate 4000ug.
Immunohistochemistry of paraffin-embedded human ovary tumor tissue slide using FNab09528 (WT1 antibody) at dilution of 1:200
- 背景介绍
- Transcription factor that plays an important role in cellular development and cell survival. Regulates the expression of numerous target genes, including EPO. Plays an essential role for development of the urogenital system. Recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3'. It has a tumor suppressor as well as an oncogenic role in tumor formation. Function may be isoform-specific: isoforms lacking the KTS motif may act as transcription factors. Isoforms containing the KTS motif may bind mRNA and play a role in mRNA metabolism or splicing. Isoform 1 has lower affinity for DNA, and can bind RNA.
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