产品

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Cytochrome c antibody

分类: 研究方向:
别称:CYC antibody, CYCS antibody, Cytochrome c antibody, cytochrome c antibody, somatic antibody, HCS antibody, THC4 antibody
货号:FNab098271反应性:Human, Mouse, Rat
宿主:Mouse验证实验:ELISA, WB, IHC
克隆性:monoclonal亚型:IgG2a
¥1900
规格:
货期: 三个工作日+顺丰&京东快递时长
  • 产品介绍
产品名称
Cytochrome c antibody
货号
FNab098271
规格
100μg
状态
liquid
纯化方法
Protein A+G purification
纯度
≥95% as determined by SDS-PAGE
克隆性
monoclonal
亚型
IgG2a
Clone ID
3G4
存储
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
免疫原信息
免疫原
Cytochrome c
别称
CYC antibody, CYCS antibody, Cytochrome c antibody, cytochrome c antibody, somatic antibody, HCS antibody, THC4 antibody
UniProt ID
P99999
分子量
12 kDa
验证实验
验证实验
ELISA, WB, IHC
建议稀释比例
WB: 1:5000-1:30000; IHC: 1:100-1:1000
验证图片
Hela cells were subjected to SDS PAGE followed by western blot with FNab098271(Cytochrome c antibody) at dilution of 1:20000
Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using FNab098271( Cytochrome c Antibody) at dilution of 1:600
背景介绍
Cytochrome c is a 12-15 kDa electron transporting protein located in the inner mitochondrial membrane. Upon apoptotic stimulation, cytochrome c can be released from mitochondria into cytoplasm, resulting in caspase-3 activation and apoptosis. Measurement of cytochrome c release from the mitochondria is useful for detection of the onset of apoptosis in cells. In addition, cytochrome c can also leave cells and be detectable in extra-cellular medium of apoptotic cells and serum of cancer patients. The level of serum cytochrome c may serve as a prognostic maker during cancer therapy.