产品
本公司产品仅供体外研究使用，不用于临床诊断
AMOT antibody
¥1900
规格：
货期：
三个工作日+顺丰&京东快递时长
- 产品名称
- AMOT antibody
- 货号
- FNab09852
- 规格
- 100μg
- 状态
- liquid
- 纯化方法
- Immunogen affinity purified
- 纯度
- ≥95% as determined by SDS-PAGE
- 克隆性
- polyclonal
- 亚型
- IgG
- 存储
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
免疫原信息
- 免疫原
- angiomotin
- 别称
- AMOT antibody, angiomotin antibody, KIAA1071 antibody
- UniProt ID
- Q4VCS5
- 分子量
- 80 kDa, 130 kDa
验证实验
- 验证实验
- ELISA, WB, IHC, IF, IP
- 建议稀释比例
- WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:50-1:500; IF: 1:20-1:200
验证图片
HEK293 cells were subjected to SDS PAGE followed by western blot with FNab09852(AMOT Antibody) at dilution of 1:1000
IP Result of anti-AMOT (IP:FNab09852, 4ug; Detection:FNab09852 1:300) with HEK-293 cells lysate 2500ug.
Immunohistochemistry of paraffin-embedded human colon cancer tissue slide using FNab09852(AMOT Antibody) at dilution of 1:200
Immunofluorescent analysis of ( -20℃ Ethanol ) fixed HEK-293 cells using FNab09852(AMOT Antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated Goat Anti-Rabbit IgG(H+L)
- 背景介绍
- Angiomotin belongs to the motin family of angiostatin binding protein. The encoded protein is expressed predominantly in endothelial cells of capillaries as well as larger vessels of the placenta where it may mediate the inhibitory effect of angiostatin on tube formation and the migration of endothelial cells toward growth factors during the formation of new blood vessels. Most abundant expression was found in placenta and skeletal muscle. AMOT has two isoforms with MW 130 kDa (p130) and 80 kDa (p80). The p130 isoform can interact with F-actin.This antibody recognizes both p130 and p80.
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