产品

本公司产品仅供体外研究使用,不用于临床诊断

P62/SQSTM1 antibody

别称:P62 antibody, sequestosome 1 antibody, SQSTM1 antibody, Ubiquitin binding protein p62 antibody
货号:FNab09853反应性:Human
宿主:mouse验证实验:ELISA, WB, IHC, IF
克隆性:monoclonal亚型:IgG2a
¥1900
规格:
货期: 三个工作日+顺丰&京东快递时长
  • 产品介绍
产品名称
P62/SQSTM1 antibody
货号
FNab09853
规格
100μg
状态
liquid
纯化方法
protein A+G purified
纯度
≥95% as determined by SDS-PAGE
克隆性
monoclonal
亚型
IgG2a
Clone ID
5H3
存储
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
免疫原信息
免疫原
sequestosome 1
别称
P62 antibody, sequestosome 1 antibody, SQSTM1 antibody, Ubiquitin binding protein p62 antibody
UniProt ID
Q13501
分子量
62 kDa
验证实验
验证实验
ELISA, WB, IHC, IF
建议稀释比例
WB: 1:1000 - 1:4000; IHC: 1:50 - 1:500; IF: 1:20 - 1:200
验证图片
HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab09853(SQSTM1 antibody) at dilution of 1:2000
Immunohistochemistry of paraffin-embedded human liver cancer tissue slide using FNab09853(SQSTM1 Antibody) at dilution of 1:100
背景介绍
This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.