产品
本公司产品仅供体外研究使用，不用于临床诊断
CD206 antibody
¥1500
规格：
货期：
三个工作日+顺丰&京东快递时长
- 产品名称
- CD206 antibody
- 货号
- FNab09912
- 规格
- 100μg
- 状态
- liquid
- 纯化方法
- Immunogen affinity purified
- 纯度
- ≥95% as determined by SDS-PAGE
- 克隆性
- polyclonal
- 亚型
- IgG
- 存储
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
免疫原信息
- 免疫原
- mannose receptor, C type 1
- 别称
- CD206 antibody, CLEC13D antibody, Macrophage mannose receptor 1 antibody, Mannose receptor antibody, mannose receptor antibody, C type 1 antibody, MMR antibody, MRC1 antibody
- UniProt ID
- P22897
- 分子量
- 166 kDa
验证实验
- 验证实验
- ELISA, WB, IHC, IF
- 建议稀释比例
- WB: 1:200-1:2000; IHC: 1:50-1:200; IF: 1:50-1:200
验证图片
Mouse liver were subjected to SDS PAGE followed by western blot with FNab09912(CD206 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human lung using FNab09912(CD206 antibody) at dilution of 1:100
- 背景介绍
- CD206, also named as MMR, CLEC13D and MRC1, is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. CD206 has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment. CD206 is a 170 kDa transmembrane protein which contains 5 domains: an amino-terminal cysteine-rich region, a fibronectin type II repeat, a series of eight tandem lectin-like carbohydrate recognition domains(responsible for the recognition of mannose and fucose), a transmembrane domain, and an intracellular carboxy-terminal tail. It is expressed on most tissue macrophages, in vitro derived dendritic cells, lymphatic and sinusoidal endothelia.
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