产品
本公司产品仅供体外研究使用，不用于临床诊断
LOXL1 antibody
¥1500
规格：
货期：
三个工作日+顺丰&京东快递时长
- 产品名称
- LOXL1 antibody
- 货号
- FNab09975
- 规格
- 100μg
- 状态
- liquid
- 纯化方法
- Immunogen affinity purified
- 纯度
- ≥95% as determined by SDS-PAGE
- 克隆性
- polyclonal
- 亚型
- IgG
- 存储
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
免疫原信息
- 免疫原
- lysyl oxidase-like 1
- 别称
- LOL antibody, LOXL antibody, LOXL1 antibody, Lysyl oxidase homolog 1 antibody, lysyl oxidase like 1 antibody, Lysyl oxidase like protein 1 antibody
- UniProt ID
- Q08397
- 分子量
- 70kDa
验证实验
- 验证实验
- ELISA, WB
- 建议稀释比例
- WB: 1:500 - 1:2000
验证图片
A549 cells were subjected to SDS PAGE followed by western blot with FNab09975(LOXL1 Antibody) at dilution of 1:1000
- 背景介绍
- This gene encodes a member of the lysyl oxidase family of proteins. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyzes the first step in the formation of crosslinks in collagen and elastin. The encoded preproprotein is proteolytically processed to generate the mature enzyme. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. Mutations in this gene are associated with exfoliation syndrome.
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