产品

本公司产品仅供体外研究使用，不用于临床诊断

LAT antibody

分类：

研究方向：

别称：	LAT antibody, LAT1 antibody, p36 38 antibody, pp36 antibody
货号：	FNab10030	反应性：	Human, Mouse
宿主：	Rabbit	验证实验：	ELISA, WB, IHC
克隆性：	polyclonal	亚型：	IgG

说明书

¥1500

规格：

货期：三个工作日+顺丰&京东快递时长

产品名称: LAT antibody
货号: FNab10030
规格: 100μg
状态: liquid
纯化方法: Immunogen affinity purified
纯度: ≥95% as determined by SDS-PAGE
克隆性: polyclonal
亚型: IgG
存储: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

免疫原信息

验证实验

验证图片

Jurkat cells were subjected to SDS PAGE followed by western blot with FNab10030(LAT antibody) at dilution of 1:1000

Immunohistochemistry of paraffin-embedded mouse spleen using FNab10030(LAT antibody) at dilution of 1:100

背景介绍: Required for TCR(T-cell antigen receptor)-and pre-TCR-mediated signaling, both in mature T-cells and during their development. Involved in FCGR3(low affinity immunoglobulin gamma Fc region receptor III)-mediated signaling in natural killer cells and FCER1(high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Couples activation of these receptors and their associated kinases with distal intracellular events such as mobilization of intracellular calcium stores, PKC activation, MAPK activation or cytoskeletal reorganization through the recruitment of PLCG1, GRB2, GRAP2, and other signaling molecules.