产品
本公司产品仅供体外研究使用，不用于临床诊断
ARHGEF1 antibody
¥1500
规格：
货期：
三个工作日+顺丰&京东快递时长
- 产品名称
- ARHGEF1 antibody
- 货号
- FNab10091
- 规格
- 100μg
- 状态
- liquid
- 纯化方法
- Immunogen affinity purified
- 纯度
- ≥95% as determined by SDS-PAGE
- 克隆性
- polyclonal
- 亚型
- IgG
- 存储
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
免疫原信息
- 免疫原
- Rho guanine nucleotide exchange factor(GEF) 1
- 别称
- ARHGEF1 antibody, GEF1 antibody, LBCL2 antibody, LSC antibody, P115 RHOGEF antibody, p115RhoGEF antibody, SUB1.5 antibody, ARHG1 antibody
- UniProt ID
- Q92888
- 分子量
- 102-110 kDa
验证实验
- 验证实验
- ELISA, IHC
- 建议稀释比例
- IHC: 1:20-1:200
验证图片
Immunohistochemistry of paraffin-embedded rat lung using FNab10091(PER2 antibody) at dilution of 1:50
- 背景介绍
- Seems to play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12(GNA12) and alpha-13(GNA13) subunits. Acts as GTPase-activating protein(GAP) for GNA12 and GNA13, and as guanine nucleotide exchange factor(GEF) for RhoA GTPase. Activated G alpha 13/GNA13 stimulates the RhoGEF activity through interaction with the RGS-like domain. This GEF activity is inhibited by binding to activated GNA12. Mediates angiotensin-2-induced RhoA activation.
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