产品
本公司产品仅供体外研究使用，不用于临床诊断
MGMT antibody
¥1500
规格：
货期：
三个工作日+顺丰&京东快递时长
- 产品名称
- MGMT antibody
- 货号
- FNab10100
- 规格
- 100μg
- 状态
- liquid
- 纯化方法
- Immunogen affinity purified
- 纯度
- ≥95% as determined by SDS-PAGE
- 克隆性
- polyclonal
- 亚型
- IgG
- 存储
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
免疫原信息
- 免疫原
- O-6-methylguanine-DNA methyltransferase
- 别称
- MGMT antibody
- UniProt ID
- P16455
- 分子量
- 22 kDa
验证实验
- 验证实验
- ELISA, IHC
- 建议稀释比例
- IHC: 1:50 - 1:500
验证图片
Immunohistochemistry of paraffin-embedded human liver cancer using FNab10100(MGMT antibody) at dilution of 1:200
- 背景介绍
- Involved in the cellular defense against the biological effects of O6-methylguanine(O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
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