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PPARA antibody

分类:
别称:hPPAR antibody, NR1C1 antibody, PPAR antibody, PPAR alpha antibody, PPARA antibody
货号:FNab10676反应性:Human, Mouse, Rat
宿主:Mouse验证实验:ELISA, WB
克隆性:monoclonal亚型:IgG1
¥1900
规格:
货期: 三个工作日+顺丰快递时长
  • 产品介绍
产品名称
PPARA antibody
货号
FNab10676
规格
100μg
状态
liquid
纯化方法
Protein A+G purification
纯度
≥95% as determined by SDS-PAGE
克隆性
monoclonal
亚型
IgG1
Clone ID
11H4
存储
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
免疫原信息
免疫原
peroxisome proliferator-activated receptor alpha
别称
hPPAR antibody, NR1C1 antibody, PPAR antibody, PPAR alpha antibody, PPARA antibody
UniProt ID
Q07869
分子量
52-55 kDa
验证实验
验证实验
ELISA, WB
建议稀释比例
WB: 1:500-1:2000
验证图片
HepG2 cells were subjected to SDS PAGE followed by western blot with FNab10676(PPARA antibody) at dilution of 1:1000
背景介绍
Ligand-activated transcription factor. Key regulator of lipid metabolism. Activated by the endogenous ligand 1-palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine(16:0/18:1-GPC). Activated by oleylethanolamide, a naturally occurring lipid that regulates satiety. Receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the ACOX1 and P450 genes. Transactivation activity requires heterodimerization with RXRA and is antagonized by NR2C2. May be required for the propagation of clock information to metabolic pathways regulated by PER2.