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PHF-1 antibody

分类:
别称:MTF2L2 antibody, PCL1 antibody, PHD finger protein 1 antibody, PHF1 antibody, PHF2 antibody, Polycomb like protein 1 antibody, Protein PHF1 antibody
货号:FNab10677反应性:Human, Mouse, Rat
宿主:Rabbit验证实验:ELISA, WB
克隆性:polyclonal亚型:IgG
¥1900
规格:
货期: 三个工作日+顺丰快递时长
  • 产品介绍
产品名称
PHF-1 antibody
货号
FNab10677
规格
100μg
状态
liquid
纯化方法
Immunogen affinity purified
纯度
≥95% as determined by SDS-PAGE
克隆性
polyclonal
亚型
IgG
存储
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
免疫原信息
免疫原
PHD finger protein 1
别称
MTF2L2 antibody, PCL1 antibody, PHD finger protein 1 antibody, PHF1 antibody, PHF2 antibody, Polycomb like protein 1 antibody, Protein PHF1 antibody
UniProt ID
O43189
分子量
62-70 kDa
验证实验
验证实验
ELISA, WB
建议稀释比例
WB: 1:500-1:2000
验证图片
Various lysates were subjected to SDS PAGE followed by western blot with FNab10677(PHF-1 antibody) at dilution of 1:1000
背景介绍
Plant homeodomain finger protein 1 (PHF1) has a specific role in histone modification and in non-homologous end joining. It is a human homolog of the Drosophila protein Polycomb-like protein. PHF1 acts by binding to H3K36me3, a mark for transcriptional activation, and recruiting the PRC2 complex: it is however unclear whether recruitment of the PRC2 complex to H3K36me3 leads to enhance or inhibit H3K27me3 methylation mediated by the PRC2 complex. PHF1 regulates also p53/TP53 stability.