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ACC1 antibody
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- 产品名称
- ACC1 antibody
- 货号
- FNab10685
- 规格
- 100μg
- 状态
- liquid
- 纯化方法
- Protein A+G purification
- 纯度
- ≥95% as determined by SDS-PAGE
- 克隆性
- monoclonal
- 亚型
- IgG2a
- Clone ID
- 9D2
- 存储
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
免疫原信息
- 免疫原
- acetyl-Coenzyme A carboxylase alpha
- 别称
- ACACA Synonyms ACAC antibody, ACACA antibody, ACC antibody, ACC1 antibody, ACCA antibody, Acetyl CoA carboxylase 1 antibody
- UniProt ID
- Q13085
- 分子量
- 270 kDa
验证实验
- 验证实验
- ELISA, WB, IHC
- 建议稀释比例
- WB: 1:2000-1:10000; IHC: 1:100-1:500
验证图片
various lysates were subjected to SDS PAGE followed by western blot with FNab10685(ACC1 antibody) at dilution of 1:2000
Immunohistochemistry of paraffin-embedded human breast cancer using FNab10685(ACC1 antibody) at dilution of 1:200
- 背景介绍
- ACACA(Acetyl-CoA carboxylase 1, ACC), also named as ACAC, ACC1 and ACCA, belongs to the biotin containing enzyme family. It catalyzes the synthesis of malonyl-CoA, which is an intermediate substrate playing a pivotal role in the regulation of fatty acid metabolism and energy production. ACACA is involved in the biosynthesis of fatty acids, and malonyl-CoA produced is used as a building block to extend the chain length of fatty acids by fatty acid synthase(FAS)(PMID:19900410). It has 4 isoforms produced by alternative promoter usage with the molecular weight between 260 kDa and 270 kDa.