产品
本公司产品仅供体外研究使用,不用于临床诊断
- 产品介绍
- 相关文献
- 产品名称
- BMP2 antibody
- 货号
- FNab00917
- 规格
- 100μg
- 状态
- liquid
- 纯化方法
- Immunogen affinity purified
- 纯度
- ≥95% as determined by SDS-PAGE
- 克隆性
- polyclonal
- 亚型
- IgG
- 存储
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
免疫原信息
- 免疫原
- bone morphogenetic protein 2
- 别称
- BMP2A antibody
- UniProt ID
- P12643
- 分子量
- 45 kDa
验证实验
- 验证实验
- ELISA, WB, IHC
- 建议稀释比例
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:100
验证图片
HeLa cells were subjected to SDS PAGE followed by western blot with FNab00917(BMP2 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human small intestine tissue slide using FNab00917 (BMP2 Antibody) at dilution of 1:50
- 背景介绍
- Bone morphogenetic protein-2 (BMP-2) is a member of the transforming growth factor-beta (TGFB) superfamily. BMP2 is synthesized as a 60 kDa precursor that is processed in the secretory pathway to a small 18 kDa monomer; 2 monomers then associate to form the active 30 kDa homodimer, which binds to its receptor. There is also a 40-45 kDa form of BMP2, as an amino-terminal propeptide. BMP2 can induce bone formation and regeneration during early embryonic development. It is involved in the hedgehog pathway, TGF beta signaling pathway, and cytokine-cytokine receptor interaction.
IF: 4.183
- 期刊名:
- International Journal of Molecular Sciences
- 作者:
- 匈牙利佩奇大学
- 发布日期:
- 2020-04-30
- 引用产品: