产品
本公司产品仅供体外研究使用，不用于临床诊断
IL-6 antibody
¥1500
规格：
货期：
三个工作日+顺丰快递时长
- 产品名称
- IL-6 antibody
- 货号
- FNab04282
- 规格
- 100μg
- 状态
- liquid
- 纯化方法
- Immunogen affinity purified
- 纯度
- ≥95% as determined by SDS-PAGE
- 克隆性
- polyclonal
- 亚型
- IgG
- 存储
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
免疫原信息
- 免疫原
- interleukin 6(interferon, beta 2)
- 别称
- B cell stimulatory factor 2 antibody, BSF 2 antibody, BSF2 antibody, CDF antibody, CTL differentiation factor antibody, HGF antibody, HSF antibody, Hybridoma growth factor antibody, IFN beta 2 antibody, IFNB2 antibody, IL 6 antibody, IL6 antibody, IL-6 antibody, Interferon beta 2 antibody, Interleukin 6 antibody
- UniProt ID
- P05231
- 分子量
- 24 kDa
验证实验
- 验证实验
- ELISA, WB, IHC, IF
- 建议稀释比例
- WB: 1:500-1:1000; IHC: 1:50-1:200; IF: 1:50-1:200
验证图片
Various lysates were subjected to SDS PAGE followed by western blot with FNab04282(Il6 Antibody) at dilution of 1:600
Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using FNab04282(IL6 Antibody) at dilution of 1:200
Immunofluorescence analysis of RAW264.7 cells using IL-6 antibody (FNab04282) at dilution of 1:100. Blue: DAPI for nuclear staining.
- 背景介绍
- Interleukin-6(IL-6) is an interleukin that acts as both a pro-inflammatory and anti-inflammatory cytokine. IL-6 protein is secreted by a variety of cell types including T cells and macrophages as phosphorylated and variably glycosylated molecule. IL-6 Plays an essential role in the final differentiation of B-cells into Ig-secreting cells involved in lymphocyte and monocyte differentiation. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. IL-6 is also considered a myokine, a cytokine produced from muscle, and is elevated in response to muscle contraction. IL-6 has been shown to interact with interleukin-6 receptor and glycoprotein 130. Additionally, IL-6 is involved in hematopoiesis, bone metabolism, and cancer progression, and has been defined an essential role in directing transition from innate to acquired immunity.
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