产品
本公司产品仅供体外研究使用，不用于临床诊断
P62/SQSTM1 antibody
¥1900
规格：
货期：
三个工作日+顺丰快递时长
- 产品名称
- P62/SQSTM1 antibody
- 货号
- FNab06087
- 规格
- 100μg
- 状态
- liquid
- 纯化方法
- Immunogen affinity purified
- 纯度
- ≥95% as determined by SDS-PAGE
- 克隆性
- polyclonal
- 亚型
- IgG
- 存储
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
免疫原信息
- 免疫原
- sequestosome 1
- 别称
- P62 antibody, sequestosome 1 antibody, SQSTM1 antibody, Ubiquitin binding protein p62 antibody
- UniProt ID
- Q13501
- 分子量
- 62 kDa
验证实验
- 验证实验
- ELISA, WB, IHC, IF, IP
- 建议稀释比例
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200; IP: 1:20 - 1:50
验证图片
HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab06087(SQSTM1 antibody) at dilution of 1:1000
IP result of anti-P62/SQSTM1(IP:FNab06087, 4ug; Detection:FNab06087 1:1000) with HEK-293 cells lysate 4000 ug
Immunohistochemistry of paraffin-embedded human esophagus using FNab06087(SQSTM1 antibody) at dilution of 1:50
- 背景介绍
- This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.
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