产品
本公司产品仅供体外研究使用，不用于临床诊断
PGK1 antibody
¥1500
规格：
货期：
三个工作日+顺丰快递时长
- 产品名称
- PGK1 antibody
- 货号
- FNab06354
- 规格
- 100μg
- 状态
- liquid
- 纯化方法
- Immunogen affinity purified
- 纯度
- ≥95% as determined by SDS-PAGE
- 克隆性
- polyclonal
- 亚型
- IgG
- 存储
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
免疫原信息
- 免疫原
- phosphoglycerate kinase 1
- 别称
- PGKA antibody
- UniProt ID
- P00558
- 分子量
- 47 kDa
验证实验
- 验证实验
- ELISA, WB, IHC, IF
- 建议稀释比例
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200
验证图片
HeLa cells were subjected to SDS PAGE followed by western blot with FNab06354(PGK1 antibody) at dilution of 1:1200
Immunohistochemistry of paraffin-embedded human esophagus using FNab06354( PGK1 Antibody) at dilution of 1:50
- 背景介绍
- The protein encoded by this gene is a glycolytic enzyme that catalyzes the conversion of 1, 3-diphosphoglycerate to 3-phosphoglycerate. The encoded protein may also act as a cofactor for polymerase alpha. Additionally, this protein is secreted by tumor cells where it participates in angiogenesis by functioning to reduce disulfide bonds in the serine protease, plasmin, which consequently leads to the release of the tumor blood vessel inhibitor angiostatin. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Deficiency of the enzyme is associated with a wide range of clinical phenotypes hemolytic anemia and neurological impairment. Pseudogenes of this gene have been defined on chromosomes 19, 21 and the X chromosome.
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