产品

本公司产品仅供体外研究使用,不用于临床诊断

Phospho-Akt(Ser473) antibody

别称:AKT antibody, AKT1 antibody, AKT1-phospho-S473 antibody, PKB antibody, PKB ALPHA antibody, PRKBA antibody, Protein kinase B antibody, Proto oncogene c Akt antibody, RAC antibody, RAC ALPHA antibody, RAC PK alpha antibody
货号:FNab06402反应性:Human, Mouse, Rat
宿主:Mouse验证实验:ELISA, IHC, WB
克隆性:monoclonal亚型:IgG1
¥2100
规格:
货期: 三个工作日+顺丰快递时长
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产品名称
Phospho-Akt(Ser473) antibody
货号
FNab06402
规格
100μg
状态
liquid
纯化方法
Protein A+G purification
纯度
≥95% as determined by SDS-PAGE
克隆性
monoclonal
亚型
IgG1
Clone ID
5H4
存储
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
免疫原信息
免疫原
v-akt murine thymoma viral oncogene homolog 1
别称
AKT antibody, AKT1 antibody, AKT1-phospho-S473 antibody, PKB antibody, PKB ALPHA antibody, PRKBA antibody, Protein kinase B antibody, Proto oncogene c Akt antibody, RAC antibody, RAC ALPHA antibody, RAC PK alpha antibody
UniProt ID
P31749
分子量
60KD
验证实验
验证实验
ELISA, IHC, WB
建议稀释比例
WB: 1:1000-1:4000; IHC: 1:50-1:200
验证图片
Jurkat cells were subjected to SDS PAGE followed by western blot with FNab06402(Phospho-Akt (S473) Antibody) at dilution of 1:2000
Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using FNab06402(Phospho-Akt (S473) Antibody) at dilution of 1:200
背景介绍
The serine-threonine protein kinase AKT1 is catalytically inactive in serum-starved primary and immortalized fibroblasts. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. This antibody detects all the members of AKT with phospho-modification.