产品
本公司产品仅供体外研究使用，不用于临床诊断
TGF-beta 1 antibody
¥1500
规格：
货期：
三个工作日+顺丰快递时长
- 产品名称
- TGF-beta 1 antibody
- 货号
- FNab08638
- 规格
- 100μg
- 状态
- liquid
- 纯化方法
- Immunogen affinity purified
- 纯度
- ≥95% as determined by SDS-PAGE
- 克隆性
- polyclonal
- 亚型
- IgG
- 存储
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
免疫原信息
- 免疫原
- transforming growth factor, beta 1
- 别称
- CED antibody, DPD1 antibody, LAP antibody, TGF beta 1 antibody, TGFB antibody, TGFB1 antibody, TGFbeta antibody, TGF-beta1 antibody, TGF-β1 antibody
- UniProt ID
- P01137?
- 分子量
- 44 kDa
验证实验
- 验证实验
- ELISA, WB, IHC
- 建议稀释比例
- WB: 1:200-1:2000; IHC: 1:50-1:500
验证图片
A549 cells were subjected to SDS PAGE followed by western blot with FNab08638(TGFB1 Antibody) at dilution of 1:600
Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using FNab08638(TGFB1 Antibody) at dilution of 1:200
- 背景介绍
- TGFB, also named as LAP and TGFB1, is a multifunctional peptide that controls proliferation, differentiation, and other functions in many cell types. TGFB acts synergistically with TGFA in inducing transformation. It also acts as a negative autocrine growth factor. Dysregulation of TGFB activation and signaling may result in apoptosis. Many cells synthesize TGFB and almost all of them have specific receptors for it. TGFB positively and negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts. It is highly expressed in bone. Mutation of TGFB are the cause of Camurati-Engelmann disease(CED) which known as progressive diaphyseal dysplasia 1(DPD1).
抗体定制服务
抗体定制服务
