产品
本公司产品仅供体外研究使用,不用于临床诊断
ZO-1 antibody
别称: | Tight junction protein 1 antibody, Tight junction protein ZO 1 antibody, TJP1 antibody, ZO 1 antibody, ZO1 antibody, ZO-1 antibody, Zona occludens protein 1 antibody, Zonula occludens protein 1 antibody | ||
货号: | FNab09750 | 反应性: | Human, Mouse, Rat |
宿主: | Rabbit | 验证实验: | ELISA, WB |
克隆性: | polyclonal | 亚型: | IgG |
¥2100
规格:
货期:
三个工作日+顺丰&京东快递时长
- 产品介绍
- 相关文献
- 产品名称
- ZO-1 antibody
- 货号
- FNab09750
- 规格
- 100μg
- 状态
- liquid
- 纯化方法
- Immunogen affinity purified
- 纯度
- ≥95% as determined by SDS-PAGE
- 克隆性
- polyclonal
- 亚型
- IgG
- 存储
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
免疫原信息
- 免疫原
- tight junction protein 1(zona occludens 1)
- 别称
- Tight junction protein 1 antibody, Tight junction protein ZO 1 antibody, TJP1 antibody, ZO 1 antibody, ZO1 antibody, ZO-1 antibody, Zona occludens protein 1 antibody, Zonula occludens protein 1 antibody
- UniProt ID
- Q07157
- 分子量
- 230kd
验证实验
- 验证实验
- ELISA, WB
- 建议稀释比例
- WB: 1:500 - 1:2000
验证图片
A431 cells were subjected to SDS PAGE followed by western blot with FNab09750(ZO1 antibody) at dilution of 1:1000
- 背景介绍
- Tight junction(or zonula occludens) form the continuous intercellular barrier between epithelial and endothelial cells, which is required to separate tissue spaces and regulate selective movement of solutes across the epithelium and endothelium(PMID: 20066090). ZO-1(also known as TJP1) is a peripheral membrane phosphoprotein located on the cytoplasmic face and is expressed in tight junctions of both epithelial and endothelial cells(PMID: 3528172). It binds the transmembrane proteins occludin and the claudins linking them to cytoskeletal actin(PMID: 17418867). ZO-1 belongs to a family of multidomain proteins known as the membrane-associated guanylate kinase homologs(MAGUKs). It is a pivotal tight junction protein and may be involved in signalling mechanisms regulating cell proliferation and differentiation(PMID: 22782886).
IF: 5.443
- 期刊名:
- Stem Cells International
- 作者:
- Asia Stem Cell Regenerative Pharmaceutical Co., Ltd.
- 发布日期:
- 2021-12-03
- 引用产品: