产品
本公司产品仅供体外研究使用，不用于临床诊断
P Glycoprotein antibody
¥1900
规格：
货期：
三个工作日+顺丰&京东快递时长
- 产品名称
- P Glycoprotein antibody
- 货号
- FNab09805
- 规格
- 100μg
- 状态
- liquid
- 纯化方法
- Immunogen affinity purified
- 纯度
- ≥95% as determined by SDS-PAGE
- 克隆性
- polyclonal
- 亚型
- IgG
- 存储
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
免疫原信息
- 免疫原
- ABCB1
- 别称
- ABCB1 antibody, CD243 antibody, GP170 antibody, MDR1 antibody, Multidrug resistance protein 1 antibody, P glycoprotein 1 antibody
- UniProt ID
- P08183
- 分子量
- 142 kDa
验证实验
- 验证实验
- ELISA, WB, IP, IHC
- 建议稀释比例
- WB: 1:200-1:1000; IP: 1:200-1:1000; IHC: 1:50-1:500
验证图片
unboiled HepG2 cells were subjected to SDS PAGE followed by western blot with FNab09805(P glycoprotein antibody) at dilution of 1:300
IP Result of anti-P glycoprotein (IP: FNab09805, 4ug; Detection: FNab09805 1:300) with human placenta tissue lysate 4000ug.
Immunohistochemistry of paraffin-embedded human liver cancer tissue slide using FNab09805(P glycoprotein antibody) at dilution of 1:500
- 背景介绍
- ABCB1(also known as P-gp/ P-glycoprotein, MDR1/multidrug-resistance 1) is a plasma membrane protein first discovered in multidrug resistant tumor cells. ABCB1 can extrude a large number of medically relevant compounds from cells and causes drug resistance. ABCB1 is expressed in a variety of human cancers as well as normal tissues including brain, and placenta. Overexpression of ABCB1 correlates with a negative prognosis in several types of cancer.
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