产品
本公司产品仅供体外研究使用，不用于临床诊断
CXCR3 antibody
¥1900
规格：
货期：
三个工作日+顺丰&京东快递时长
- 产品名称
- CXCR3 antibody
- 货号
- FNab09859
- 规格
- 100μg
- 状态
- liquid
- 纯化方法
- Immunogen affinity purified
- 纯度
- ≥95% as determined by SDS-PAGE
- 克隆性
- polyclonal
- 亚型
- IgG
- 存储
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
免疫原信息
- 免疫原
- CXCR3
- 别称
- CD182 antibody, CD183 antibody, CKR-L2 antibody, CMKAR3 antibody, GPR9 antibody, IP10-R antibody, Mig-R antibody, MigR antibody
- UniProt ID
- P49682
- 分子量
- 45 kDa
验证实验
- 验证实验
- ELISA, WB, IHC
- 建议稀释比例
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:100
验证图片
K562 cells were subjected to SDS PAGE followed by western blot with FNab09859(CXCR3 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded mouse heart using FNab09859(CXCR3 antibody) at dilution of 1:100
- 背景介绍
- This gene encodes a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9/Mig (monokine induced by interferon-g), CXCL10/IP10 (interferon-g-inducible 10 kDa protein) and CXCL11/I-TAC (interferon-inducible T cell a-chemoattractant). Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the isoforms (CXCR3-B) shows high affinity binding to chemokine, CXCL4/PF4 (PMID:12782716).
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