产品
本公司产品仅供体外研究使用，不用于临床诊断
Fibronectin antibody
¥1500
规格：
货期：
三个工作日+顺丰&京东快递时长
- 产品名称
- Fibronectin antibody
- 货号
- FNab10458
- 规格
- 100μg
- 状态
- liquid
- 纯化方法
- Immunogen affinity purified
- 纯度
- ≥95% as determined by SDS-PAGE
- 克隆性
- polyclonal
- 亚型
- IgG
- 存储
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
免疫原信息
- 免疫原
- fibronectin 1
- 别称
- CIG antibody, Cold insoluble globulin antibody, DKFZp686F10164 antibody, DKFZp686H0342 antibody, DKFZp686I1370 antibody, DKFZp686O13149 antibody, ED B antibody, Fibronectin antibody, fibronectin 1 antibody, FINC antibody, FN antibody, FN1 antibody, FNZ antibody, GFND antibody, GFND2 antibody, LETS antibody, MSF antibody
- UniProt ID
- P02751
- 分子量
- 220-270 kDa
验证实验
- 验证实验
- ELISA, WB, IHC
- 建议稀释比例
- WB: 1:200-1:2000; IHC: 1:50-1:200
验证图片
U-87MG cells were subjected to SDS PAGE followed by western blot with FNab10458(FN1 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human colon cancer using FNab10458(FN1 antibody) at dilution of 1:50
- 背景介绍
- Fibronectin 1(FN1) is a high molecular weight glycoprotein which exists in both a soluble form in plasma(plasma FN1) and other body fluids and an insoluble form in the extracellular matrix(cellular FN1). Plasma FN1(dimeric form) is secreted by hepatocytes. Cellular FN(dimeric or cross-linked multimeric forms), made by fibroblasts, epithelial and other cell types, is deposited as fibrils in the extracellular matrix. FN1 binds to cell surfaces through integrins and to various compounds including collagen, fibrin and heparin. It is involved in cell adhesion and migration processes including embryogenesis, wound healing, hemostasis, host defense, and metastasis.(PMID: 7276612; 12244123; 12847088)
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