产品
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GSDMD antibody
¥2100
规格：
货期：
三个工作日+顺丰快递时长
- 产品名称
- GSDMD antibody
- 货号
- FNab03670
- 规格
- 100μg
- 状态
- liquid
- 纯化方法
- Immunogen affinity purified
- 纯度
- ≥95% as determined by SDS-PAGE
- 克隆性
- polyclonal
- 亚型
- IgG
- 存储
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
免疫原信息
- 免疫原
- gasdermin D
- 别称
- DF5L antibody, DFNA5L antibody, FKSG10 antibody, FLJ12150 antibody, gasdermin D antibody, GSDMD antibody, GSDMDC1 antibody
- UniProt ID
- P57764
- 分子量
- 50-53 kDa
验证实验
- 验证实验
- ELISA, WB, IHC, IF
- 建议稀释比例
- WB: 1:200-1:2000; IHC: 1:20-1:200; IF: 1:10-1:100
验证图片
Jurkat cells were subjected to SDS PAGE followed by western blot with FNab03670(GSDMD Antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded human skin using FNab03670(GSDMD antibody) at dilution of 1:50
- 背景介绍
- GSDMD is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. GSDMD has been suggested to act as a tumor suppressor. Recently, GSDMD is identified as a new component of inflammasomes, and it is an executor of pyroptosis and required for interleukin-1β secretion. Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death.
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