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IL1 beta antibody

别称:IL1 beta antibody, Catabolin antibody, IL 1 antibody, IL 1 beta antibody, IL1 BETA antibody, IL1B antibody, IL1beta antibody, IL1F2 antibody, IL-1β antibody, Interleukin 1 beta antibody, interleukin 1 antibody, beta antibody
货号:FNab04209反应性:Human, Mouse, Rat
宿主:Rabbit验证实验:ELISA, IHC, WB
克隆性:polyclonal亚型:IgG
¥1500
规格:
货期: 三个工作日+顺丰快递时长
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产品名称
IL1 beta antibody
货号
FNab04209
规格
100μg
状态
liquid
纯化方法
Immunogen affinity purified
纯度
≥95% as determined by SDS-PAGE
克隆性
polyclonal
亚型
IgG
存储
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
免疫原信息
免疫原
interleukin 1, beta
别称
IL1 beta antibody, Catabolin antibody, IL 1 antibody, IL 1 beta antibody, IL1 BETA antibody, IL1B antibody, IL1beta antibody, IL1F2 antibody, IL-1β antibody, Interleukin 1 beta antibody, interleukin 1 antibody, beta antibody
UniProt ID
P01584
分子量
17,35-40 kDa
验证实验
验证实验
ELISA, IHC, WB
建议稀释比例
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
验证图片
A549 cells were subjected to SDS PAGE followed by western blot with FNab04209( IL1B Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded rat lung using FNab04209(IL1B antibody) at dilution of 1:50
背景介绍
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.