产品
本公司产品仅供体外研究使用，不用于临床诊断
Caspase 3 antibody
¥1500
规格：
货期：
三个工作日+顺丰&京东快递时长
- 产品名称
- Caspase 3 antibody
- 货号
- FNab10013
- 规格
- 100μg
- 状态
- liquid
- 纯化方法
- Immunogen affinity purified
- 纯度
- ≥95% as determined by SDS-PAGE
- 克隆性
- polyclonal
- 亚型
- IgG
- 存储
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
免疫原信息
- 免疫原
- caspase 3, apoptosis-related cysteine peptidase
- 别称
- Apopain antibody, CASP 3 antibody, CASP3 antibody, Caspase 3 antibody, Caspase 3/p17 antibody, Caspase3 antibody, CPP 32 antibody, CPP32 antibody, CPP32B antibody, Cysteine protease CPP32 antibody, Protein Yama antibody, SCA 1 antibody, SREBP cleavage activity 1 antibody
- UniProt ID
- P42574
- 分子量
- 32-35 kDa, 17 kDa
验证实验
- 验证实验
- ELISA, WB, IHC, IF
- 建议稀释比例
- WB: 1:200-1:2000; IHC: 1:50-1:500; IF: 1:50-1:200
验证图片
Jurkat cells were subjected to SDS PAGE followed by western blot with FNab10013(CASP3 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded mouse heart tissue slide using FNab10013(CASP3 Antibody) at dilution of 1:100
Immunofluorescent analysis of ( -20°C Ethanol) fixed HeLa cells using FNab10013 (caspase 3 antibody) at dilution of 1:50 and FITC-Conjugated Goat Anti-rabbit IgG(H+L)
- 背景介绍
- Caspase 3, also named as CPP32, SCA-1 and Apopain, belongs to the peptidase C14A family. Caspase 3 is involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase(PARP) at a '216-Asp-|-Gly-217' bond. Caspase 3 cleaves and activates sterol regulatory element binding proteins(SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6,-7 and-9. Caspase 3 is involved in the cleavage of huntingtin. The antibody can recognize p17 and p32 of Caspase 3.
抗体定制服务
抗体定制服务
