白细胞介素是指一类分子结构和生物学功能已基本明确,具有重要调节作用而统一命名的细胞因子,它和血细胞生长因子同属细胞因子。两者相互协调,相互作用,共同完成造血和免疫调节功能。截至目前,发现的IL成员至少达38个,分别命名为IL-1~IL38。
白细胞介素
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白细胞介素是指一类分子结构和生物学功能已基本明确,具有重要调节作用而统一命名的细胞因子,它和血细胞生长因子同属细胞因子。两者相互协调,相互作用,共同完成造血和免疫调节功能。截至目前,发现的IL成员至少达38个,分别命名为IL-1~IL38。
根据细胞因子的结构同源性可将成员分为几个蛋白质家族,如IL-1家族、IL-6家族、IL-10家族、肿瘤坏死因子家族和造血因子家族等。
分类 |
简介 |
成员 |
IL-1家族 |
IL-1家族有11个成员,可称作IL-1F1~IL-1F11;其中绝大多数是促炎性细胞因子 |
IL-1α、IL-1β、IL-1Ra、IL-18、IL-36Ra、IL-36a、IL-37、IL-36β、IL-36γ、IL-38和IL-33 |
IL-2家族(γc家族) |
有5个成员,是信号传导都依赖于γ c链的一组细胞因子 |
IL-2、IL-4、IL-13、IL-15和IL-21 |
趋化因子家族 |
IL-3和一些不属于白细胞介素的细胞因子归类为趋化因子家族 |
IL-3 |
趋化因子家族C-X-C/α亚族 |
IL-8和一些不属于白细胞介素的细胞因子归类为趋化因子家族此亚族 |
IL-8 |
IL-12/IL-6家族 |
IL-12家族/IL-6家族包含5个成员 |
IL-6、IL-12、IL-23、IL-27(IL-30)、IL-35 |
IL-10家族 |
IL-10家族是II类细胞因子的一个亚家族,对免疫系统发挥着多种多样的调节作用 |
IL-10、IL-19、IL-20、IL-22、IL-24和IL-26 |
IL-17家族 |
IL-17家族有两个白介素成员 |
IL-17和IL-25 (IL-17E) |
其他 |
其余的白细胞介素不明确属于任何一个家族 |
IL-5、IL-7、IL-9、IL-11、IL-14、IL-16、IL-31、IL-32 |
IL-1家族有11个成员,是一种主要由活化的巨噬细胞产生的细胞因子,由IL 1α和IL-1β两种蛋白组成。IL-1家族(IL-1F)具有古老的进化史。基于氨基酸序列的保守性、基因结构的同源性和三维结构,已鉴定出11个IL-1成员。包括 7 种促炎激动剂(IL-1α、IL-1β、IL-18、IL-33、IL-36a、IL-36b 和 IL-36g)和 4 种具有抗炎活性的拮抗剂(IL-1Ra、IL-36Ra、IL-37 和 IL-38)。
种属 |
货号 |
产品名称 |
灵敏度 |
检测范围 |
目录价96T |
Human |
2.344pg/ml |
3.906-250pg/ml |
¥2,480 |
||
Mouse |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
||
Rat |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
||
Human |
2.344pg/ml |
3.906-250pg/ml |
¥2,480 |
||
Mouse |
7.5pg/ml |
12.5-800pg/ml |
¥2,480 |
||
Rat |
18.75pg/ml |
31.25-2000pg/ml |
¥2,480 |
||
Human |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
||
Mouse |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
||
Rat |
18.75pg/ml |
31.25-2000pg/ml |
¥2,480 |
||
Human |
0.094ng/ml |
0.156-10ng/ml |
¥2,480 |
||
Mouse |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
||
Human |
18.75pg/ml |
31.25-2000pg/ml |
¥2,480 |
||
Human |
18.75pg/ml |
31.25-2000pg/ml |
¥2,480 |
||
Mouse |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
||
Human |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
||
Human |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
||
Mouse |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
||
Rat |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
IL-2家族(γc家族) 有5个成员,是信号传导都依赖于γc链的一组细胞因子:IL-2、IL-4、IL-13、IL-15和IL-21
种属 |
货号 |
产品名称 |
灵敏度 |
检测范围 |
目录价96T |
Human |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
||
Mouse |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
||
Rat |
18.75pg/ml |
31.25-2000pg/ml |
¥2,480 |
||
Human |
18.75pg/ml |
31.25-2000pg/ml |
¥2,480 |
||
Mouse |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
||
Rat |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
||
Human |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
||
Mouse |
18.75pg/ml |
31.25-2000pg/ml |
¥2,480 |
||
Rat |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
||
Human |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
||
Mouse |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
||
Rat |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
||
Human |
37.5pg/ml |
62.5-4000pg/ml |
¥2,480 |
||
Mouse |
18.75pg/ml |
31.25-2000pg/ml |
¥2,480 |
||
Rat |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
趋化因子家族:IL-3和一些不属于白细胞介素的细胞因子归类为趋化因子家族
种属 |
货号 |
产品名称 |
灵敏度 |
检测范围 |
目录价 96T |
Human |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
||
Mouse |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
||
Rat |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
趋化因子家族C-X-C/α亚族:IL-8和一些不属于白细胞介素的细胞因子归类为趋化因子家族此亚族
种属 |
货号 |
产品名称 |
灵敏度 |
检测范围 |
目录价96T |
Human |
18.75pg/ml |
31.25-2000pg/ml |
¥2,480 |
||
Mouse |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
IL-12家族/IL-6家族包含5个成员:IL-6、IL-12、IL-23、IL-27(IL-30)、IL-35
|
|
|
|
AQ-H0201-B |
EH0201 |
EM0121 |
ER0042 |
品牌 |
种属 |
货号 |
产品名称 |
灵敏度 |
检测范围 |
FineTest |
Human |
46fg/ml |
0.078-5pg/ml |
||
FineTest |
Human |
2.813pg/ml |
4.688-300pg/ml |
||
R&D |
Human |
D6050 |
Human IL-6 Quantikine ELISA Kit |
0.7 pg/mL |
3.1-300pg/mL |
FineTest |
Mouse |
9.375pg/ml |
15.625-1000pg/ml |
||
R&D |
Mouse |
M6000B |
Mouse IL-6 Quantikine ELISA Kit |
1.8 pg/mL |
7.8-500 pg/mL |
FineTest |
Rat |
37.5pg/ml |
62.5-4000pg/ml |
||
R&D |
Rat |
R6000B |
Rat IL-6 Quantikine ELISA Kit |
36 pg/mL |
62.5-4000pg/mL |
种属 |
货号 |
产品名称 |
灵敏度 |
检测范围 |
目录价96T |
Rat |
37.5pg/ml |
62.5-4000pg/ml |
¥2,480 |
||
Human |
2.813pg/ml |
4.688-300pg/ml |
¥2,480 |
||
Mouse |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
||
Human |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
||
Mouse |
4.688pg/ml |
7.813-500pg/ml |
¥2,480 |
||
Rat |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
||
Human |
23.438pg/ml |
39.063-2500pg/ml |
¥2,480 |
||
Mouse |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
||
Rat |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
||
Human |
0.094ng/ml |
0.156-10ng/ml |
¥2,480 |
||
Mouse |
4.688pg/ml |
7.813-500pg/ml |
¥2,480 |
||
Rat |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
||
Human |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
||
Mouse |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
IL-10家族是II类细胞因子的一个亚家族,对免疫系统发挥着多种多样的调节作用 IL-10、IL-19、IL-20、IL-22、IL-24和IL-26
种属 |
货号 |
产品名称 |
灵敏度 |
检测范围 |
目录价96T |
Human |
4.688pg/ml |
7.813-500pg/ml |
¥2,480 |
||
Mouse |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
||
Rat |
18.75pg/ml |
31.25-2000pg/ml |
¥2,480 |
||
Human |
18.75pg/ml |
31.25-2000pg/ml |
¥2,480 |
||
Mouse |
18.75pg/ml |
31.25-2000pg/ml |
¥2,480 |
||
Rat |
23.438pg/ml |
39.063-2500pg/ml |
¥2,480 |
||
Human |
37.5pg/ml |
62.5-4000pg/ml |
¥2,480 |
||
Mouse |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
||
Rat |
18.75pg/ml |
31.25-2000pg/ml |
¥2,480 |
||
Human |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
||
Rat |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
||
Mouse |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
||
Human |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
||
Mouse |
18.75pg/ml |
31.25-2000pg/ml |
¥2,480 |
||
Rat |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
||
Human |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
IL-17家族有两个白介素成员 IL-17和IL-25 (IL-17E)
种属 |
货号 |
产品名称 |
灵敏度 |
检测范围 |
目录价 96T |
Human |
18.75pg/ml |
31.25-2000pg/ml |
¥2,480 |
||
Rat |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
||
Mouse |
4.688pg/ml |
7.813-500pg/ml |
¥2,480 |
||
Human |
18.75pg/ml |
31.25-2000pg/ml |
¥2,480 |
||
Mouse |
18.75pg/ml |
31.25-2000pg/ml |
¥2,480 |
||
Human |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
||
Human |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
||
Human |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
||
Mouse |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
||
Human |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
||
Mouse |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
||
Rat |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
其余的白细胞介素不明确属于任何一个家族 IL-5、IL-7、IL-9、IL-11、IL-14、IL-16、IL-31、IL-32
种属 |
货号 |
产品名称 |
灵敏度 |
检测范围 |
目录价96T |
Human |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
||
Mouse |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
||
Rat |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
||
Human |
4.688pg/ml |
7.813-500pg/ml |
¥2,480 |
||
Rat |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
||
Mouse |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
||
Human |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
||
Rat |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
||
Mouse |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
||
Human |
18.75pg/ml |
31.25-2000pg/ml |
¥2,480 |
||
Mouse |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
||
Rat |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
||
Human |
18.75pg/ml |
31.25-2000pg/ml |
¥2,480 |
||
Mouse |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
||
Rat |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
||
Human |
4.688pg/ml |
7.813-500pg/ml |
¥2,480 |
||
Mouse |
4.688pg/ml |
7.813-500pg/ml |
¥2,480 |
||
Human |
9.375pg/ml |
15.625-1000pg/ml |
¥2,480 |
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