产品
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FITC Anti-Human IL-10 Antibody(JES3-9D7)
| 规格 | 价格 |
|---|---|
| 100T | RMB ¥3080 |
| 20T | RMB ¥1260 |
货期：
三个工作日+顺丰快递时长
- 产品名称
- FITC Anti-Human IL-10 Antibody(JES3-9D7)
- 货号
- FITC-30088
- 状态
- liquid
- 偶联物
- FITC
- 克隆性
- monoclonal
- 亚型
- IgG1, kappa
- Clone ID
- JES3-9D7
- 存储
- PBS with 0. 1% sodium azide, 1%BSA, pH 7.3, 2-8℃ for 12 months (Avoid repeated freeze / thaw cycles.)
免疫原信息
- 免疫原
- interleukin 10
- 别称
- Interleukin-10 (IL-10)|Cytokine synthesis inhibitory factor (CSIF)|IL10 antibody
- UniProt ID
- P22301
验证实验
- 验证实验
- FC
- 建议稀释比例
- Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
验证图片
HEK293T cells transiently transfected with pcDNA3.1 plasmid encoding Human IL-10 gene are stained with FITC Anti-Human IL-10 Antibody(filled red histogram) or FITC Rat IgG1, κ Isotype Control (empty black histogram).
- 背景介绍
- The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.
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