产品
本公司产品仅供体外研究使用，不用于临床诊断
EIF4EBP1 antibody
| 规格 | 价格 |
|---|---|
| 100μg | RMB ¥1900 |
| 50μg | RMB ¥1140 |
货期：
三个工作日+顺丰快递时长
- 产品名称
- EIF4EBP1 antibody
- 货号
- FNab00006
- 规格
- 100μg
- 状态
- liquid
- 纯化方法
- Protein A+G purification
- 纯度
- ≥95% as determined by SDS-PAGE
- 克隆性
- monoclonal
- 亚型
- IgG2b
- Clone ID
- 6C4
- 存储
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
免疫原信息
- 免疫原
- eukaryotic translation initiation factor 4E binding protein 1
- 别称
- Eukaryotic translation initiation factor 4E-binding protein 1 (4E-BP1 antibody, eIF4E-binding protein 1)|Phosphorylated heat- and acid-stable protein regulated by insulin 1 (PHAS-I)|EIF4EBP1 antibody
- UniProt ID
- Q13541
- 分子量
- 12 kDa
验证实验
- 验证实验
- ELISA, WB, IF
- 建议稀释比例
- WB: 1:500-1:2000; IF: 1:20-1:200
验证图片
K-562 cells were subjected to SDS PAGE followed by western blot with FNab00006(4EBP1 antibody) at dilution of 1:2000
Immunofluorescent analysis of Hela cells using FNab00006 ( 4EBP1 Antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated Goat Anti-Mouse IgG(H+L)
- 背景介绍
- Eukaryotic translation initiation factor 4E-binding protein 1(4EBP1), is a member of 4EBPs family, which regulate the translation of a subset of mRNA by competing with eIF4G for binding to eIF4E, thus preventing the assembly of the eIF4F complex. The eIF4F facilitates the recruitment of other translation initiation factors to form the complex and then initiates cap-dependent translation.4EBP1 also mediates the regulation of protein translation by growth factors, hormones and other stimuli that signal through the MAP kinase and mTORC1 pathways. There are three forms of 4EBP1, alpha, beta and gamma.
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