human placenta tissue were subjected to SDS PAGE followed by western blot with FNab00116(ACTA2 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human oophoroma using FNab00116(ACTA2 antibody) at dilution of 1:50
背景介绍
The protein encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Defects in this gene cause aortic aneurysm familial thoracic type 6. Multiple alternatively spliced variants, encoding the same protein, have been identified.