Jurkat cells were subjected to SDS PAGE followed by western blot with FNab00131(ACVRL1 antibody) at dilution of 1:400
IP Result of anti-ACVRL1 (IP:FNab00131, 4ug; Detection:FNab00131 1:300) with Jurkat cells lysate 2400ug.
Immunohistochemistry of paraffin-embedded human heart tissue slide using FNab00131(ACVRL1 Antibody) at dilution of 1:200
背景介绍
Type I receptor for TGF-beta family ligands BMP9/GDF2 and BMP10 and important regulator of normal blood vessel development. On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. May bind activin as well.