Aldo-keto reductase family 1 member C4|3-alpha-hydroxysteroid dehydrogenase type I (3-alpha-HSD1)|3alpha-hydroxysteroid 3-dehydrogenase|Chlordecone reductase (CDR)|Dihydrodiol dehydrogenase 4 (DD-4 antibody, DD4)|HAKRA|AKR1C4|CHDR antibody
货号:
FNab00263
反应性:
Human, Mouse, Rat
宿主:
Rabbit
验证实验:
ELISA, WB, IF
克隆性:
polyclonal
亚型:
IgG
规格
价格
100μg
RMB ¥1900
50μg
RMB ¥1140
货期:
三个工作日+顺丰快递时长
产品介绍
实验结果
实验条件
常见问题
产品名称
AKR1C4 antibody
货号
FNab00263
规格
100μg
状态
liquid
纯化方法
Immunogen affinity purified
纯度
≥95% as determined by SDS-PAGE
克隆性
polyclonal
亚型
IgG
存储
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
免疫原信息
免疫原
aldo-keto reductase family 1, member C4(chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4)
别称
Aldo-keto reductase family 1 member C4|3-alpha-hydroxysteroid dehydrogenase type I (3-alpha-HSD1)|3alpha-hydroxysteroid 3-dehydrogenase|Chlordecone reductase (CDR)|Dihydrodiol dehydrogenase 4 (DD-4 antibody, DD4)|HAKRA|AKR1C4|CHDR antibody
MCF7 cells were subjected to SDS PAGE followed by western blot with FNab00263(AKR1C4 antibody) at dilution of 1:500
背景介绍
Catalyzes the transformation of the potent androgen dihydrotestosterone(DHT) into the less active form, 5-alpha-androstan-3-alpha,17-beta-diol(3-alpha-diol). Also has some 20-alpha-hydroxysteroid dehydrogenase activity. The biotransformation of the pesticide chlordecone(kepone) to its corresponding alcohol leads to increased biliary excretion of the pesticide and concomitant reduction of its neurotoxicity since bile is the major excretory route.