human heart tissue were subjected to SDS PAGE followed by western blot with FNab00304(ALDOC antibody) at dilution of 1:10000
Immunohistochemistry of paraffin-embedded human liver tissue slide using FNab00304(ALDOC Antibody) at dilution of 1:200 . heat mediated antigen retrieved with Tris-EDTA buffer(pH9).
背景介绍
Fructose-bisphosphate aldolase C(ALDOC) reversibly cleaves FBP and F1-P to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate and is strongly expressed in mammalian brain together with ALDOA and is alsopresent in the heart and spleen of some species(PMID:9363598). It is involed in glycolysis as an important enzyme. Phospholipase D2 and inositol 1,4,5-triphosphate interact with ALDOC in signal transduction. Meanwhile, the protein expression of ALDOC has been reported to be regulated in brain tumor, hepatomas, and lung cancer(PMID:21548097).