Angiotensinogen|Serpin A8|Angiotensin-1 Alternative names: Angiotensin 1-10|Angiotensin I (Ang I)|Angiotensin-2 Alternative names: Angiotensin 1-8|Angiotensin II (Ang II)|Angiotensin-3 Alternative names: Angiotensin 2-8|Angiotensin III (Ang III)|Des-Asp[1]-angiotensin II|Angiotensin-4 Alternative names: Angiotensin 3-8|Angiotensin IV (Ang IV)|Angiotensin 1-9|Angiotensin 1-7|Angiotensin 1-5|Angiotensin 1-4|AGT|SERPINA8 antibody
货号:
FNab00394
反应性:
Human
宿主:
Rabbit
验证实验:
ELISA, WB, IF, IHC
克隆性:
polyclonal
亚型:
IgG
规格
价格
100μg
RMB ¥1750
50μg
RMB ¥1050
货期:
三个工作日+顺丰快递时长
产品介绍
实验结果
实验条件
常见问题
产品名称
AGT antibody
货号
FNab00394
规格
100μg
状态
liquid
纯化方法
Immunogen affinity purified
纯度
≥95% as determined by SDS-PAGE
克隆性
polyclonal
亚型
IgG
存储
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
免疫原信息
免疫原
angiotensinogen(serpin peptidase inhibitor, clade A, member 8)
别称
Angiotensinogen|Serpin A8|Angiotensin-1 Alternative names: Angiotensin 1-10|Angiotensin I (Ang I)|Angiotensin-2 Alternative names: Angiotensin 1-8|Angiotensin II (Ang II)|Angiotensin-3 Alternative names: Angiotensin 2-8|Angiotensin III (Ang III)|Des-Asp[1]-angiotensin II|Angiotensin-4 Alternative names: Angiotensin 3-8|Angiotensin IV (Ang IV)|Angiotensin 1-9|Angiotensin 1-7|Angiotensin 1-5|Angiotensin 1-4|AGT|SERPINA8 antibody
human plasma tissue were subjected to SDS PAGE followed by western blot with FNab00394(AGT antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human hepatocirrhosis tissue slide using FNab00394(AGT Antibody) at dilution of 1:50
背景介绍
Angiotensinogen is a precursor of angiotensin II(Ang II), is expressed and synthesized largely in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. It has a key role in mediating vascular constriction and regulating salt and fluid homeostasis. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme(ACE) to generate the physiologically active enzyme angiotensin II. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease.