A375 cells were subjected to SDS PAGE followed by western blot with FNab00398(ANGPTL3 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded mouse kidney using FNab00398(ANGPTL3 antibody) at dilution of 1:100
背景介绍
This gene encodes a member of a family of secreted proteins that function in angiogenesis. The encoded protein, which is expressed predominantly in the liver, is further processed into an N-terminal coiled-coil domain-containing chain and a C-terminal fibrinogen chain. The N-terminal chain is important for lipid metabolism, while the C-terminal chain may be involved in angiogenesis. Mutations in this gene cause familial hypobetalipoproteinemia type 2.