产品
本公司产品仅供体外研究使用，不用于临床诊断
ANGPTL4 antibody
| 规格 | 价格 |
|---|---|
| 100μg | RMB ¥1900 |
| 50μg | RMB ¥1140 |
货期：
三个工作日+顺丰快递时长
- 产品名称
- ANGPTL4 antibody
- 货号
- FNab00399
- 规格
- 100μg
- 状态
- liquid
- 纯化方法
- Immunogen affinity purified
- 纯度
- ≥95% as determined by SDS-PAGE
- 克隆性
- polyclonal
- 亚型
- IgG
- 存储
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
免疫原信息
- 免疫原
- angiopoietin-like 4
- 别称
- Angiopoietin-related protein 4|Angiopoietin-like protein 4|Hepatic fibrinogen/angiopoietin-related protein (HFARP)|ANGPTL4 N-terminal chain|ANGPTL4 C-terminal chain|ANGPTL4|ARP4|HFARP|PGAR antibody
- UniProt ID
- Q9BY76
- 分子量
- 45 kDa
验证实验
- 验证实验
- ELISA, IHC, IF, IP, WB
- 建议稀释比例
- WB: 1:200-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200; IP: 1:200-1:2000
验证图片
HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab00399(ANGPTL4 Antibody) at dilution of 1:1000
IP Result of anti-ANGPTL4 (IP:FNab00399, 4ug; Detection:FNab00399 1:500) with mouse heart tissue lysate 4000ug.
Immunohistochemistry of paraffin-embedded human kidney slide using FNab00399(ANGPTL4 Antibody) at dilution of 1:50
Immunofluorescent analysis of ( -20°C Ethanol) fixed HEK-293 cells using FNab00399 (ANGPTL4 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated Goat Anti-Rabbit IgG(H+L)
- 背景介绍
- Protein with hypoxia-induced expression in endothelial cells. May act as a regulator of angiogenesis and modulate tumorigenesis. Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. May exert a protective function on endothelial cells through an endocrine action. It is directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity. In response to hypoxia, the unprocessed form of the protein accumulates in the subendothelial extracellular matrix(ECM). The matrix-associated and immobilized unprocessed form limits the formation of actin stress fibers and focal contacts in the adhering endothelial cells and inhibits their adhesion. It also decreases motility of endothelial cells and inhibits the sprouting and tube formation(By similarity).
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