NIH/3T3 cells were subjected to SDS PAGE followed by western blot with FNab00466(AP3M1 antibody) at dilution of 1:400
IP Result of anti-AP3M1 (IP:FNab00466, 4ug; Detection:FNab00466 1:300) with NIH/3T3 cells lysate 1200ug.
背景介绍
Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.