human brain tissue were subjected to SDS PAGE followed by western blot with FNab00467(AP3M2 antibody) at dilution of 1:200
Immunohistochemistry of paraffin-embedded mouse brain tissue slide using FNab00467(AP3M2 Antibody) at dilution of 1:50
背景介绍
Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.