HUVEC cells were subjected to SDS PAGE followed by western blot with FNab00578( ARL4C Antibody) at dilution of 1:600
Immunohistochemistry of paraffin-embedded human colon cancer tissue slide using FNab00578(ARL4C Antibody ) at dilution of 1:200
背景介绍
Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors(GEF) and GTPase-activating proteins(GAP). GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit. May be involved in transport between a perinuclear compartment and the plasma membrane, apparently linked to the ABCA1-mediated cholesterol secretion pathway. Recruits CYTH1, CYTH2, CYTH3 and CYTH4 to the plasma membrane in the GDP-bound form. Regulates the microtubule-dependent intracellular vesicular transport from early endosome to recycling endosome process.