human liver tissue were subjected to SDS PAGE followed by western blot with FNab00636(ASGR2 antibody) at dilution of 1:400
IP Result of anti-ASGR2 (IP:FNab00636, 4ug; Detection:FNab00636 1:300) with L02 cells lysate 1800ug.
背景介绍
Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor recognizes terminal galactose and N-acetylgalactosamine units. After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle, where receptor and ligand are disassociated. The receptor then returns to the cell membrane surface.