HepG2 cells were subjected to SDS PAGE followed by western blot with FNab00652(ASTN2 Antibody) at dilution of 1:300
Immunohistochemistry of paraffin-embedded human brain tissue slide using FNab00652(ASTN2 Antibody) at dilution of 1:50
背景介绍
Mediates recycling of the neuronal cell adhesion molecule ASTN1 to the anterior pole of the cell membrane in migrating neurons. Promotes ASTN1 internalization and intracellular transport of endocytosed ASTN1(By similarity). Selectively binds inositol-4,5-bisphosphate, inositol-3,4,5-trisphosphate and inositol-1,3,4,5-tetrakisphosphate, suggesting it is recruited to membranes that contain lipids with a phosphoinositide headgroup(Ref.6).