产品
本公司产品仅供体外研究使用，不用于临床诊断
BACE1 antibody
| 规格 | 价格 |
|---|---|
| 100μg | RMB ¥1900 |
| 50μg | RMB ¥1140 |
货期：
三个工作日+顺丰快递时长
- 产品名称
- BACE1 antibody
- 货号
- FNab00781
- 规格
- 100μg
- 状态
- liquid
- 纯化方法
- Immunogen affinity purified
- 纯度
- ≥95% as determined by SDS-PAGE
- 克隆性
- polyclonal
- 亚型
- IgG
- 存储
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
免疫原信息
- 免疫原
- beta-site APP-cleaving enzyme 1
- 别称
- Beta-secretase 1|Aspartyl protease 2 (ASP2 antibody, Asp 2)|Beta-site amyloid precursor protein cleaving enzyme 1 (Beta-site APP cleaving enzyme 1)|Memapsin-2|Membrane-associated aspartic protease 2|BACE1|BACE|KIAA1149 antibody
- UniProt ID
- P56817
- 分子量
- 70-75 kDa
验证实验
- 验证实验
- ELISA, WB, IP, IHC
- 建议稀释比例
- WB: 1:500-1:1000; IP: 1:500-1:1000; IHC: 1:100-1:400
验证图片
mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab00781(BACE1 antibody) at dilution of 1:500
IP Result of anti-BACE1 (IP:FNab00781, 3ug; Detection:FNab00781 1:500) with mouse brain tissue lysate 5000ug.
Immunohistochemistry of paraffin-embedded mouse brain tissue slide using FNab00781(BACE1 Antibody) at dilution of 1:200 heat mediated antigen retrieved with Tris-EDTA buffer(pH9).
- 背景介绍
- Responsible for the proteolytic processing of the amyloid precursor protein(APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.
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