产品
本公司产品仅供体外研究使用,不用于临床诊断
- 产品介绍
- 相关文献
- 产品名称
- BAK antibody
- 货号
- FNab00796
- 规格
- 100μg
- 状态
- liquid
- 纯化方法
- Immunogen affinity purified
- 纯度
- ≥95% as determined by SDS-PAGE
- 克隆性
- polyclonal
- 亚型
- IgG
- 存储
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
免疫原信息
- 免疫原
- BCL2-antagonist/killer 1
- 别称
- Apoptosis regulator BAK antibody, BAK antibody, BAK LIKE antibody, BAK1 antibody, CDN1 antibody
- UniProt ID
- Q16611
- 分子量
- 26 kDa
验证实验
- 验证实验
- ELISA, WB, IHC
- 建议稀释比例
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:100
验证图片
A431 cells were subjected to SDS PAGE followed by western blot with FNab00796(BAK antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using FNab00796( BAK Antibody) at dilution of 1:200
- 背景介绍
- The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.
IF: 6.543
- 期刊名:
- Oxidative Medicine and Cellular Longevity
- 发布日期:
- 2021-09-10
- 引用产品: