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BAK antibody

别称:Apoptosis regulator BAK antibody, BAK antibody, BAK LIKE antibody, BAK1 antibody, CDN1 antibody
货号:FNab00796反应性:Human, Mouse, Rat
宿主:Rabbit验证实验:ELISA, WB, IHC
克隆性:polyclonal亚型:IgG
¥1900
规格:
货期: 三个工作日+顺丰快递时长
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产品名称
BAK antibody
货号
FNab00796
规格
100μg
状态
liquid
纯化方法
Immunogen affinity purified
纯度
≥95% as determined by SDS-PAGE
克隆性
polyclonal
亚型
IgG
存储
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
免疫原信息
免疫原
BCL2-antagonist/killer 1
别称
Apoptosis regulator BAK antibody, BAK antibody, BAK LIKE antibody, BAK1 antibody, CDN1 antibody
UniProt ID
Q16611
分子量
26 kDa
验证实验
验证实验
ELISA, WB, IHC
建议稀释比例
WB: 1:500 - 1:2000; IHC: 1:50 - 1:100
验证图片
A431 cells were subjected to SDS PAGE followed by western blot with FNab00796(BAK antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using FNab00796( BAK Antibody) at dilution of 1:200
背景介绍
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.