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GAPDH antibody

别称:GAPD antibody, G3PD antibody, GAPDH antibody, OK/SW cl.12 antibody
货号:FNab03342反应性:Human, Mouse, Rat
宿主:Rabbit验证实验:ELISA, IHC, WB
克隆性:polyclonal亚型:IgG
¥750
规格:
货期: 三个工作日+顺丰快递时长
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产品名称
GAPDH antibody
货号
FNab03342
规格
100μg
状态
liquid
纯化方法
Immunogen affinity purified
纯度
≥95% as determined by SDS-PAGE
克隆性
polyclonal
亚型
IgG
存储
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
免疫原信息
免疫原
glyceraldehyde-3-phosphate dehydrogenase
别称
GAPD antibody, G3PD antibody, GAPDH antibody, OK/SW cl.12 antibody
UniProt ID
P04406
分子量
36 kDa
验证实验
验证实验
ELISA, IHC, WB
建议稀释比例
WB: 1:1000-1:5000; IHC: 1:100-1:500
验证图片
various lysates were subjected to SDS PAGE followed by western blot with FNab03342(GAPDH antibody) at dilution of 1:2000
Immunohistochemistry of paraffin-embedded human colon cancer using FNab03342(GAPDH antibody) at dilution of 1:100
背景介绍
Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are probably due to the nitrosylase activity that mediates cysteine S-nitrosylation of nuclear target proteins such as SIRT1, HDAC2 and PRKDC. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubules(By similarity). Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate(G3P) into 3-phospho-D-glyceroyl phosphate. Component of the GAIT(gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma treatment assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs(such as ceruplasmin) and suppresses their translation.
IF: 4.06
期刊名:
American Journal of Translational Research
发布日期:
2021-07-30
引用产品:
IF: 1.785
期刊名:
Experimental and Therapeutic Medicine
发布日期:
2020-06-26
引用产品:
IF: 1.4
期刊名:
Iranian Journal of Public Health
作者:
General Surgery Department, Nanjing Red Cross Hospital, Nanjing City, Jiangsu Province, 210000, China
发布日期:
2023-08-11
引用产品: