HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab00922(BMPR1A Antibody) at dilution of 1:1000
IP Result of anti-BMPR1A (IP:FNab00922, 4ug; Detection:FNab00922 1:500) with HEK-293 cells lysate 2000ug.
Immunofluorescent analysis of HeLa cells using FNab00922 (BMPR1A antibody) at dilution of 1:25 and Alexa Fluor 594-conjugated Goat Anti-Rabbit IgG(H+L)
背景介绍
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP2, BMP4, GDF5 and GDF6. Positively regulates chondrocyte differentiation through GDF5 interaction. Mediates induction of adipogenesis by GDF6.