产品
本公司产品仅供体外研究使用，不用于临床诊断
CACNA1B antibody
| 规格 | 价格 |
|---|---|
| 100μg | RMB ¥1900 |
| 50μg | RMB ¥1140 |
货期：
三个工作日+顺丰快递时长
- 产品名称
- CACNA1B antibody
- 货号
- FNab01171
- 规格
- 100μg
- 状态
- liquid
- 纯化方法
- Immunogen affinity purified
- 纯度
- ≥95% as determined by SDS-PAGE
- 克隆性
- polyclonal
- 亚型
- IgG
- 存储
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
免疫原信息
- 免疫原
- calcium channel, voltage-dependent, N type, alpha 1B subunit
- 别称
- Voltage-dependent N-type calcium channel subunit alpha-1B|Brain calcium channel III (BIII)|Calcium channel antibody, L type antibody, alpha-1 polypeptide isoform 5|Voltage-gated calcium channel subunit alpha Cav2.2|CACNA1B|CACH5|CACNL1A5 antibody
- UniProt ID
- Q00975
- 分子量
- 262 kDa
验证实验
- 验证实验
- ELISA, WB, IHC
- 建议稀释比例
- WB: 1:200-1:1000; IHC: 1:50-1:500
验证图片
mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab01171(CACNA1B antibody) at dilution of 1:300
Immunohistochemistry of paraffin-embedded mouse brain tissue slide using FNab01171(CACNA1B Antibody) at dilution of 1:100 heat mediated antigen retrieved with Tris-EDTA buffer(pH9).
- 背景介绍
- Voltage-sensitive calcium channels(VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. N-type calcium channels belong to the 'high-voltage activated'(HVA) group and are blocked by omega-conotoxin-GVIA(omega-CTx-GVIA) and by omega-agatoxin-IIIA(omega-Aga-IIIA). They are however insensitive to dihydropyridines(DHP), and omega-agatoxin-IVA(omega-Aga-IVA). Calcium channels containing alpha-1B subunit may play a role in directed migration of immature neurons.
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