Hela cells were subjected to SDS PAGE followed by western blot with FNab01259(CAPZB antibody) at dilution of 1:3000
背景介绍
F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments(barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins(such as gelsolin and severin), these proteins do not sever actin filaments. Plays a role in the regulation of cell morphology and cytoskeletal organization.