产品
本公司产品仅供体外研究使用，不用于临床诊断
CASP8 antibody
| 规格 | 价格 |
|---|---|
| 100μg | RMB ¥1750 |
| 50μg | RMB ¥1050 |
货期：
三个工作日+顺丰快递时长
- 产品名称
- CASP8 antibody
- 货号
- FNab01293
- 规格
- 100μg
- 状态
- liquid
- 纯化方法
- Immunogen affinity purified
- 纯度
- ≥95% as determined by SDS-PAGE
- 克隆性
- polyclonal
- 亚型
- IgG
- 存储
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
免疫原信息
- 免疫原
- caspase 8, apoptosis-related cysteine peptidase
- 别称
- Caspase-8 (CASP-8)|Apoptotic cysteine protease|Apoptotic protease Mch-5|CAP4|FADD-homologous ICE/ced-3-like protease|FADD-like ICE (FLICE)|ICE-like apoptotic protease 5|MORT1-associated ced-3 homolog (MACH)|Caspase-8 subunit p18|Caspase-8 subunit p10|CASP8|MCH5 antibody
- UniProt ID
- Q14790
- 分子量
- 50-55 kDa, 25-32 kDa
验证实验
- 验证实验
- ELISA, WB, IHC, IP, IF
- 建议稀释比例
- WB: 1:200-1:2000; IP: 1:200-1:2000; IHC: 1:50-1:100; IF: 1:10-1:100
验证图片
HepG2 cells were subjected to SDS PAGE followed by western blot with FNab01293(CASP8 antibody) at dilution of 1:1000
IP Result of anti-CASP8 (IP:FNab01293, 3ug; Detection:FNab01293 1:500) with HeLa cells lysate 2500ug.
Immunohistochemistry of paraffin-embedded human lymphoma using FNab01293(CASP8 antibody) at dilution of 1:50
Immunofluorescent analysis of ( -20℃ Ethanol ) fixed HepG2 cells using FNab01293 (Caspase 8 Antibody)at dilution of 1:25 and Rhodamine-Goat anti-Rabbit IgG
- 背景介绍
- Caspase 8, also named as MCH5, MACH, FLICE, and CAP4, belongs to the peptidase C14A family. It may participate in the GZMB apoptotic pathways and functions as an upstream regulator in a-bisabolol-induced apoptosis. Caspase 8 catalyzes an essential intermediate step in the ubiquitination and proteasome-mediated degradation of IRF3(PMID:21816816). It may control diabetic embryopathy-associated apoptosis via Caspase 8 is expressed as nine isoforms by alternative splicing with the molecular mass from 26 kDa to 62 kDa. This antibodycan recognize pro-and cleaved-caspase 8.
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