HT-1080 cells were subjected to SDS PAGE followed by western blot with FNab01302(CAT-Specific antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human hepatocirrhosis using FNab01302(CAT-Specific antibody) at dilution of 1:100
背景介绍
CAT(Catalase) belongs to the catalase family. It is involved in catabolic pathway of activated oxygen species and free radical detoxification and the catalase overexpression has a protective role against UVB irradiation by preventing DNA damage mediated by the late ROS increase. Mammalian catalase of approximately 240 kD occurs as a complex of 4 identical subunits, each of which contains 526 amino acid residues(PMID:19122680). Defects in CAT are the cause of acatalasemia(ACATLAS). This antibody is specific to CAT.