mouse liver tissue were subjected to SDS PAGE followed by western blot with FNab01334(CBY1 antibody) at dilution of 1:500
IP Result of anti-CBY1 (IP:FNab01334, 4ug; Detection:FNab01334 1:500) with mouse liver tissue lysate 4000ug.
Immunohistochemistry of paraffin-embedded human kidney using FNab01334(CBY1 antibody) at dilution of 1:50
背景介绍
Inhibits the Wnt/Wingless pathway by binding to CTNNB1/beta-catenin and inhibiting beta-catenin-mediated transcriptional activation through competition with TCF/LEF transcription factors. Has also been shown to play a role in regulating the intracellular trafficking of polycystin-2/PKD2 and possibly of other intracellular proteins. Promotes adipocyte and cardiomyocyte differentiation.